PNGase F PRIME™

Especially Optimized for Mass Spec Imaging

N-Zyme Scientifics is a leading resource for MS-based spatial glycan tissue imaging and any other application that requires highly active and stable endoglycosidases.

N-Zyme Scientifics is a development and supply company located at the Pennsylvania Biotechnology Center of Bucks County, one of the premier Biotechnology Centers in the Country. We specialize in enzymes used in Glycobiology-based applications and research in Pharmaceuticals, Diagnostics, Drug Discovery and Biologics. Our products are especially designed for advanced applications, particularly those using MALDI-Glycan Mass Spectrometry Spatial Imaging, UPLC/HPLC, and Hydrophilic Interaction Chromatography (HILIC). Learn more about our company and its unique product offerings in greater detail below.

Our Product Superiority


No matter what type of enzyme you need, our team at N-Zyme Scientifics can provide you with the best quality products on the market today. That’s why we are the leading choice for a variety of industry applications including Pharmaceuticals, Diagnostics, Drug Discovery and Biologics, just to name a few. If you are ready to see the difference top quality enzymes make in your research, reach out to our team at N-Zyme today. 



Publications About Our Enzymes

Publications Featuring
Our Enzymes

THE EFFECT OF MOLECULAR SIGNATURES IN THE HIGH MORTALITY RATE FOUND IN EPITHELIAL OVARIAN CANCER (EOC)

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N-ZYME’S PNGASE F PRIME™ HELPS RESEARCHERS CREATE A NOVEL BIOMARKER FOR LIVER FIBROSIS

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PLEASE REFER TO OUR PUBLICATIONS TAB WHERE YOU WILL FIND MANY ADDITIONAL ARTICLES FROM OTHER GLYCOMICS-RELATED RESEARCH TOPICS

ACTIVITY

In the simplest terms, enzymes are biological catalysts. Our enzymes are all incredibly active, meaning they are consistent in producing their desired results during research and experiments

STABILITY

Our enzymes are incredibly stable, retaining their structure through storage, isolation, temperature changes and more. 

CONCENTRATION

Enzymes are combined with substrates to balance their effectiveness and their cost. Our enzymes are always highly concentrated so they work as intended every time.

UTILITY

Our enzymes have a great amount of utility, making them function well in a variety of different settings and projects.

Why Use N-Zyme Scientifics?

Since the company's inception, our team at N-Zyme Scientifics has been producing and distributing some of the best enzymes available on the market. We are trusted by large scale companies in a variety of industries ranging from pharmaceutical brands to diagnostic companies. This is because they know that our enzymes are well-researched, safe, thoughtfully produced, and distributed quickly as needed.


N-Zyme Scientifics was founded in 2013 to initially produce and sell PNGase F PRIME™, a high-performance version of Peptide-N-Glycosidase F. Use of this product in some cases (i.e., protein specific) eliminates the need to denature protein samples before glycan analysis, saving valuable time and money in addition to obtaining significantly better-quality data. Since the introduction of our PNGase F PRIME™ to the market, we have released several new products that have all been extensively tested and fine-tuned for mass spectrometry spatial imaging-based applications. Spatial glycan tissue imaging provides important information on the complex cellular interactions involved in cellular transformation and disease progression. Glycosylation of cellular proteins are biomarkers for these changes and can delineate boundaries between healthy cells and those undergoing transformation. N-Zyme Scientifics is a leader in the field of Glycan Spatial-Imaging and has developed enzymes specifically for imaging applications. The PNGase F PRIME-LY™ ULTRA was specifically engineered and formulated to give the highest fine structure resolution in glycan tissue imaging studies of complex structures. (See Publications: In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains.).


Currently, our products can be purchased directly from our valued distributors located in North America, Europe and Asia. By improving the results you get from your research as well as making it more efficient and cost effective, our enzymes are the best choice available on the market today.

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